BRAIN RESEARCH

Neuvo LTM EEG (Epilepsy Long Term Monitoring)

The Ultimate Long-term EEG Monitoring System The Neuvo is a member of the Compumedics family of amplifiers and software platforms that harmoniously integrates into the systems for efficient workflow, enhancing productivity and promoting accurate clinical outcomes. The Neuvo is based on the well-known and respected SynAmps2 research amplifier targeting clinical applications such as Long Term EEG Monitoring (LTM).

Neuvo – The Ultimate Long-term EEG Monitoring System

When the Epilepsy Monitoring Unit demands performance, Neuvo delivers. Built on the technology platform of the leading amplifier technology in the brain research world, Neuvo is capable of high density, high sampling rate recording with all channels sampled simultaneously, eliminating sample-and-hold circuitry providing superior data quality.

High-Definition EEG

A DC-coupled, digital amplifier system with a high input range and 24-bit resolution providing amplification and digitization of electroencephalographic physiologic signals from surface, cortical and depth electrodes. The amplifier provides 40 channels (32 isolated high-frequency referential channels, 8 bipolar channels), an integrated pulse-oximeter and event button input. The unit has a POE 100BASE-TX network connection for both power and communication.

Signal Processing and Source Localization Multi-Modal Neuroimaging Suite

The history of the CURRY® software is well known. Throughout the world, CURRY® has the well deserved reputation as the most advanced and comprehensive tool for Multimodal Neuroimaging. CURRY’s strength has historically been combining functional data such as EEG and MEG with structural data from MRI and CT to optimize source reconstruction.

Compumedics Neuroscan’s CURRY® software is FDA-cleared and CE-marked.

It features a complete set of tools for efficient EEG/MEG/ERP recording, review, and multi-modal integration – presented in a modern and clean user interface.
Over three decades of research and collaboration with leading brain research laboratories and Epilepsy units around the
world have resulted in proven features and functionality that continue to advance the field.

The SynAmps RT is seamlessly compatible with all of our other systems. SynAmps RT was designed with specific engineering considerations to provide the best possible recordings in the MRI. SynAmps RT uses the same trigger connector that the original SynAmps and NuAmps use, so there is no need to modify your existing stimulus protocols.

Highlights

-SynAmps RTis a 70 channel amplifier system, consisting of 64 monopolar, 4 bipolar, and 2 high-level input channels (for receiving voltage outputs from other equipment) per headbox. Each channel has a dedicated 24 bit A-to-D converter, to ensure the most accurate sampling available.

-Up to four head boxes can be combined with a single System Unit, creating a 256 channel system. Combine two System Units to create a super-high density system.

-SynAmps RTis a true DC amplifier, allowing you to record slow potentials with no high pass filtering.

-Sampling rates up to 20,000Hz (synchronized across all channels) let you record the fastest activity such as ABRs (maximum low pass filter is 3500Hz).

-Low noise 24 bit A-to-D converters allow for low gain to be used while still maintaining the resolution and a broad dynamic range (making saturation almost impossible).

-Clock synchronizationwith MR scanner triggers allows precise reduction of gradient artifact, without the need for fast sampling rates.

-Active Noise Cancellationensures accurate recordings even in the most hostile electromagnetic environments.

-De-blocking Circuitryallows for recording of TMS and other high intensity stimuli without affecting the integrity of the data.

-Input impedanceof 10 GOhm.

-Common Mode Rejection Ratioof 110 dB.

MagLink system is used for obtaining integrated EEG and ERP recordings inside the fMRI. This second-generation system improves on the original Opti-Link system by increasing the bandwidth and eliminating the pre-amplifier and optical coupling. The passive MagLink system provides the ability to record during the pulse sequence without compromising the raw EEG data. MagLink, in conjunction with Neuroscan amplifiers has successfully recorded EEG data through the pulse sequence in up to 3 Tesla MRI scanners. The CURRY 7 Acquisition and Signal Processing modules provide powerful features for on-line and off-line reduction of the ballistocardiogram and pulse sequence artifact, while retaining the integrity of the EEG. Post-processing tools allow ERP’s to be extracted, which can then be subjected to source localization and compared with the fMRI.

The gradient artifact that is injected into the EEG data can be reduced by a number of different strategies that are included in the CURRY 7 software. Having a variety of data processing methods available is critical to account for the different artifacts that are encountered. The individual artifact signatures vary based on the type of pulse sequence, magnet type and strength, the electrode impedance, even the quality of the shim on a particular day. Neuroscan’s correction methods can correct the EEG data under a variety of parameters.

“Complete, Integrated and Simple  system to record high quality of EEG and ERP Simultaneously with fMRI”

MicroMagLink system; the next generation  technology for simultaneous EEG/fMRI data acquisition – simple The MicroMagLink is based on the concept that often the simplest solution is best. The MicroMagLink keeps all active electronics outside the MRI chamber; all that is placed in MRI chamber is a special electrode cap, a cable, and a fiber optic pulseometer to provide timing for ballistocardiogram suppression. By keeping the active electronic components in the control room, we provide the best possible signal amplification without any compromises.

The MicroMagLink system consists of a precisely engineering electrode placement system with cabling that includes inline RF filtering to ensure that all signals recorded inside the MRI are uncontaminated by any sources outside the shielded MRI chamber. Using our SynAmps RT amplifier, data sampling rates up to 20,000 kHz perchannel are possible. But with the inherent capability of SynAmps amplifiers to synchronize internal clocking to external sources, data sample rates as low as 500 Hzmay be sufficient to provide high quality suppression of gradient sequence artifact.

Following ASTM standards, MicroMagLink electrodes have been engineered and tested to comply with required standards for heating, displacement and torsion up to 3 Tesla. With a single attachment to the penetration panel, the MicroMaglink may routinely be installed and removed quickly. This portability allows a single MicroMaglink to be easily deployed to any magnet in your MRI facility, or used to collect EEG simultaneously with MEG.

Curry NeuroImaging Suite

The MicroMagLink is integrated with the Curry NeuroImaging Suite, which now  includes a data acquisition module for capturing EEG data recorded in the MRI. By incorporating data acquisition into the Curry platform, all stages of EEG/ERP data recording and analysis, including source reconstruction, and co-registration with MRI, fMRI and other neuroimaging modalities are handled in a single platform. An advanced set of signal processing methods can be employed both online and offline to suppress both gradient and ballistocardiogram artifact.

Stim2 is the next evolutionary step in stimulus presentation and experimental design. Running within the Windows XP (only) environment, Stim2 retains the functionality and timing of the original DOS-based STIM, but with a contemporary user interface and numerous expanded features.

Stim2 is a complete software environment for custom stimulus and task design as well as presentation. The Stim2 system can be integrated in fMRI, MEG, and other functional neuro-imaging applications. The software provides a familiar menu-driven interface in which to design and present visual and auditory stimulation paradigms.

Stim2’s powerful and intuitive design translates into a short learning curve and quick implementation. The modules make it easy to design and execute your stimuli with the greatest precision, and the wide array of pre-packaged stimuli ensures fast integration into your research.

Stim2is comprised of 14 task modules, a generic programmable module (Gentask), a sound file editor, and an image file converter. The task modules may be categorized into Motor, Perceptual, Attention, Memory, and Cognitive tasks, many of which have neuropsychological similarity (Tapping, Stroop, Categories, Card Sorting, etc.). The Gentask program includes an interface for creating and presenting almost any type of visual, auditory, or combined task and recording behavioral responses. Gentask has been used for a variety of experiments including auditory P300, N400, MMN, CNV, picture memory, and many more. The Gentask Editor makes creating, modifying and debugging sequences files much easier. TheSound Editor program is used for recording, editing, and presenting digital sound segments. The Image Converter module will convert less familiar formats into commonly encountered types of graphics files (BMP, JPG, PNG, TIF, etc.) that can then be presented.

 

Configuration:

There are two versions of Stim2: Stim2 Complete, which uses specially designed hardware, and a Software Only version that uses the hardware in the computer. The Complete system includes the 4-button STIM Response Pad, software/hardware control of the decibel levels (precise dB levels), and the STIM microphone. Keyboard and mouse responses are available with both systems; the STIM Response Pad provides the most accurately timed responses. The Software Only version may be adequate for some situations; however, the Complete system is generally preferred. It has additional flexibility and control, and it is likely that long range development will favor the Complete system.

Stim2 interfaces seamlessly with CURRY 7 and SCAN, as well as any of our amplifiers: SynAmps2, SynAmps RT, or NuAmps.